Drug dosages, whether calculated via the ratio (rainbow), proportion, formulae or dimensional analysis method are determined by various factors. These factors include the weight of the patient and the route of administration. Both weight and route of drug administration are terrain related parameters.
The Germ-Terrain duality theory of disease states that the etiology of certain diseases/diseased states is better explained as a complex interplay between germs and the inherent anatomical/physiological integrity of the body cells.
It argues that the etiology of certain diseases is not fully explained merely by the presence of germs (Germ Theory) or by a mere loss of cellular integrity (Terrain Theory). As a result the prevention and treatment of such diseases should focus not just on fighting germs but on maintaining/restoring the anatomical/physiological cellular integrity. The Germ-Terrain duality theory is a harmonization of the current Germ Theory (popularized by Loius Pasteur) and the hitherto discarded Terrain Theory (popularized by Pierre Bechamp). [1-2]